Study discusses the genetic basis for familial hypercholesterolemia (FH) in some Libyan patients at Tripoli city, examining the distribution of variants that associated with mutations in exon 12 of low density lipoprotein receptor (LDL-R) gene on chromosome 19. Genetic analysis were done using polymerases chain reaction-single strand conformation polymorphism (PCR-SSCP) based on DNA technique, to detect splicing defects of the LDL-R gene in exon 12 on chromosome 19, among some Libyans patients probably have heterozygous familial hypercholesterol-emia (HeFH). The patient’svolunteer’s participants in this study were from Tajjora National Cardiac Center, Endocrine and Diabetic Hospital in Tripoli. The study showed the presence of the splicing defects (1845 +11 C>G)in the exon 12 of the LDL-R gene on chromosome 19 in patients with hyperchol-esterolemia and ischemic heart disease, as they have family history in hypercholesterolemia and other secondary causes to heart disease such as diabetic, hypertension, chest pain, and obesity. Frequency of HeFH Libyan patients was (0.86%), and the significant of statistical analysis were{p-value>0.05}, which considered high according to clinical diagnostic criteria for HeFH. As well as detection the single nucleotide polymorphisms (SNP) (1773C>T) that alter the exon splicing efficiency, because it is associated with an emerging of the functional genetic variants for mutations in exon-12, where results of molecular diagnosis confirmed that occurrence the mutation of (LDL-R gene) relates to premature coronary artery diseases(P-CAD). arabic 35 English 137
Soomia Ahmed Ali Al-Haddad(1-2016)

Thirty-one seabird species are found in Malaysia; a few still breed on rocky outcrops and small islands in the southern Seribuat Archipelago. A century-long egg harvest by local fishermen in the area is believed to have caused extirpation of several breeding populations. To update the status of seabirds in the southern section of the Seribuat Archipelago, a two-day survey was conducted in August 2017. Twenty-two islands were selected and surveyed using boat observation and colony visits. In total, over 6 200 birds were counted, representing five tern species: Bridled Tern Onychoprion anaethetus, Black-naped Tern Sterna sumatrana, Great Crested Tern Thalasseus bergii, Roseate Tern Sterna dougallii, and the Lesser Crested Tern T. bengalensis. The first two species are confirmed breeders, whereas the remaining species are either passage migrants or unconfirmed breeders. The survey led to the rediscovery of a small population of Roseate Terns at Pulau Yu (one of the species' two historic breeding sites in Malaysia). The islands surveyed are not legally protected (except for the Pulau Tinggi group). The protection of selected sites is highly recommended to conserve these remaining seabird populations.
Abdulmula Abdumagid Alhadi Hamza(4-2019)

Because of a lack of systematic surveys since the 1950s, information on seabird diversity and the status of seabird colonies along the east coast of Peninsular Malaysia is mostly outdated. The Seribuat Archipelago is composed of many islands, which are located off Pahang state in the north and Johor state in the south. The northern section of the archipelago was surveyed during July-September 2017 to document active seabird colony sites and to assess species richness and the potential threats facing these colonies. Seven islands were found to host significant numbers of terns (Black-naped Terns Sterna sumatrana, Bridled Terns Onychoprion anaethetus, Greater Crested Terns Thalasseus bergii, Lesser Frigatebirds Fregata ariel, and other bird species. We provide details of each site and its suitability for seabirds. Pulau Labas and Pulau Tokong Bahara have the highest species richness (five species each) followed by Pulau Tokong Burung and Pulau Gut (four species each). Tokong Burung (made up of three islands) hosts the largest colony of Bridled Terns in the region, with more than 10 000 pairs estimated, making it one of the largest colonies of the species in Southeast Asia. Egg harvesting by local fishermen, human disturbance, marine litter, and oil pollution are the main threats to seabirds in the Seribuat Archipelago. We make recommendations regarding measures needed for further protection of the area.
Abdulmula Abdumagid Alhadi Hamza(4-2020)