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منشورات مختارة

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Prevalence of Metabolic Syndrome and its Components in Nondiabetic Libyan Females

Background: The metabolic syndrome (MS) is defined as a cluster of cardiovascular risk factors, including central obesity, dysglycemia, hypertension (HPN), elevated triglycerides (TGs), and reduced high-density lipoprotein cholesterol (HDL-C). MS increases the risk of cardiovascular disease and all-cause mortality. Objective: This study aims to estimate the prevalence of MS and its components among nondiabetic Libyan females using the definition proposed by National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III). Methods: A total of 122 randomly selected nondiabetic Libyan females were included in the study. Detailed medical history was obtained from all participants. Blood pressure, weight, height, waist and hip circumference were measured. Body mass index and waist–hip ratio were calculated. Fasting blood glucose (FBG) and lipid profile were collected. Standard oral glucose tolerance test with 75 GM glucose was performed. The MS was defined by ATP III and International Diabetes Federation criteria. Results: According to NCEP definition, the prevalence of the MS in the study group was 42.6%. The most common component was abdominal obesity (67.2%). FBG was ≥ 100 mg/dl in 47.5%. The prevalence of both HPN and low HDL-C was 45.9%. About 26.2% of the participants have their TG ≥ 150 mg/dl; all were MS patients. Conclusions: The prevalence of MS and cardiovascular risk factors were high among Libyan females. Public health authorities and health-care providers should implement strategies for prevention, screening, and management of cardiovascular risk factors to reduce the burden of its potential complications
Hawa Juma El-Shareif(4-2018)
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Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 Antibodies among People Living with HIV: A Cross-sectional Study from Tripoli University Hospital

Background/Aims: Patients with preexisting morbidities(e.g., malignancy, posttransplant, and heart failure) are recognized to be at increased risk of severe acute respiratory syndrome coronavirus‑2 (SARS‑CoV‑2) infection, as well as increased risk of mortality after infection. However, there are conflicting data on the susceptibility and prevalence of infection among people living with HIV (PLWH), with higher, lower, and equal prevalence to the general population were reported. The aim of this study was to assess the prevalence of SARS‑CoV‑2 antibodies among PLWH who are attending clinical care at the Department of Infectious Diseases of Tripoli University Hospital. Materials and Methods: A cross‑sectional study conducted during the period from October 01, 2021 to December 01, 2021 at the (Department of Infectious Diseases) outpatient clinic of Tripoli University Hospital. The OnSite Coronavirus Disease 2019 IgG/IgM Rapid Test (CTK Biotech, San Diego County, California, USA) was used to determine the presence of antibodies against the spike protein of SARS‑CoV‑2 in the collected serum samples. The test results were reported as “Negative” or “Positive” as per the manufacturer’s instructions. Results: A total of 108 PLWH were included in the study. Sixty‑nine (64%) were male, and the mean age for participants was 44 years. Specific IgG/IgM antibodies for SARS‑CoV‑2 were detected in 31 individuals, representing a seroprevalence of 28.7%. Conclusions: High seroprevalence of SARS‑CoV‑2 antibodies among nonvaccinated PLWH attending clinical care at Tripoli University Hospital. They require pritorization on vaccination and boosting
Nader Shalaka(12-2021)
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Takayasu's arteritis in a Libyan female

Takayasu’s arteritis (TA) is a large‑vessel vasculitis that involves the aorta and its major branches. Renal arteries are frequently involved, usually with renovascular hypertension. The prevalence of TA in Arabs is low. A study of the epidemiological and clinical features of TA in Arabs included 197 identified patients between 1995 and 2012 and none of them was Libyan. We report a 61‑year‑old Libyan woman in whom TA manifested with hypokalemia and arterial hypertension. Previous ultrasound showed renal size asymmetry raised the possibility of renal artery stenosis. The diagnosis of TA was confirmed by magnetic resonance angiography, which showed a thickened abdominal aortic wall, occlusions of the left renal artery and left common iliac artery, stenosis of the right common iliac artery, and stenosis of both subclavian arteries. TA is rarely encountered in Arabs. However, the disease must be considered in patients who present with renovascular hypertension, in a context of other autoimmune disorders. arabic 6 English 33
Hawa Juma El-Shareif(1-2019)
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