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Clinicopathological features of differentiated thyroid carcinoma referred to radioiodine therapy at Tripoli Medical Center

Objectives: The objective of this study is to study the demographic, clinicopathological features, and geographical distribution of differentiated thyroid cancer (DTC) among Libyan patients referred from all parts of the country to the nuclear medicine department, for radioactive iodine (RAI) therapy.Materials and Methods: Retrospective review of medical records of 265 patients with differentiated thyroid carcinoma (DTC) referred to RAI therapy in the Nuclear Medicine Branch‑Tripoli Medical Center, in the period from May 2005 to October 2010. The data analyzed included sex, age at the time of diagnosis, the city of residence, pathological diagnosis, the extent of disease, and types of treatment.Results: There were 225 (84.9%) females and 40 (15.1%) males giving a sex ratio of 5.6:1. The mean age of males at diagnosis was 51.2 ± 14.8 (range 24–78) years and  the  mean age  of  the  females was  44.6 ± 15.6 (range 10–95) years. Two  hundred and  twenty‑three (84.2%) had  papillary thyroid cancer (PTC), 31 (11.7%) had  follicular thyroid cancer, 3 (1.1%) had  Hurthle cell  thyroid cancer, and  2 (0.8%) had follicular‑insular thyroid cancer. About 43 (16.2%) had  a  history of  multinodular goiter, and  3 (1.1%) Hashimoto’s thyroiditis. From data  collected, cervical lymph node metastases were found in 45 (17.0%), and distal metastases in 27 (10.2%).Conclusions: PTC was the most common type of DTC. DTC was more common among females. The current study showed that the disease tends to occur at an older age, and with less cervical lymph node metastases than previously reported.
Hawa Juma El-Shareif(3-2018)
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The diagnostic performance of chest computed tomography scanning in the diagnosis of coronavirus disease 2019 compared to polymerase chain reaction: A retrospective study of 1240 cases from Tripoli University Hospital, Libya

OBJECTIVE: The increasing prevalence of suspected cases of coronavirus disease 2019 (COVID-19) presenting to emergency departments (EDs) requires a rapid and reliable triaging tool. The diagnostic performance of chest computed tomography (CT) has yet to be validated for triaging cases in the ED. We aimed to assess the diagnostic performance of chest CT compared to GeneXpert Xpress Xpert severe acute respiratory syndrome coronavirus 2 test in rapidly diagnosing COVID-19 among patients with respiratory symptoms presenting to the ED. MATERIALS AND METHODS: This was a retrospective, single-center study at Tripoli University Hospital including cases with respiratory symptoms who underwent chest CT as well as polymerase chain reaction (PCR) testing for suspected COVID-19 between May 18 and August 18, 2020. RESULTS: A total of 1240 cases were included, among whom 570 had radiologically evident COVID-19 on chest CT (46%). Five hundred and sixty-five cases had positive PCR results (45.6%), of whom 557 had radiologically evident COVID-19 on chest CT (97.7%). The calculated accuracy, sensitivity, specificity, positive predictive value, and negative predictive value were 98%, 98.5%, 98%, 97.7%, and 98.8%, respectively, in relation to the PCR results. CONCLUSION: During the current pandemic, chest CT is a quick and reliable diagnostic tool for COVID-19 in the ED.
Nader Shalaka(11-2021)
Publisher's website

Risk calculation of developing type 2 diabetes in Libyan adults

The aim of this study was to identify nationals at risk of developing type 2 diabetes within the next 10 years in some areas across Tripoli Health Authority in Libya. In this questionnaire‐based survey, a total of 400 Libyan nationals of both genders were randomly selected from seven areas across the central area of Tripoli Health Authority (Soug El‐Juma, Zawet Dahmani, Al‐Furnaj, Ain Zara, Al‐Madena Centre, Al‐Dhahra Centre, and Noflean). All participants approached (400) completed the study and responded to the items of the survey. Based on a modified Finnish Type 2 Diabetes Risk Score test (FINDRISC), 129 (32.3%) were categorised as either at moderate or at high/very high risk of developing diabetes within the next 10 years of life. Among the 129 participants at risk, body mass index was >25 kg/m2 in 125 (96.9%) and waist circumferences were high (>88 cm for females;>102 cm for males) in almost 45% of the women and 22% of the men. We found that in the sample studied the risk of developing diabetes was clear, and there is no doubt that interventions to reduce such risk are a priority rather than a need. Diabetes has a great impact on the health of the nation and also on the future resources of the country in managing the disease and its complications; a health education/health campaign could be one good answer to tackle the problem. arabic 9 English 54
Hawa Juma El-Shareif(6-2009)
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