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Takayasu's arteritis in a Libyan female

Takayasu’s arteritis (TA) is a large‑vessel vasculitis that involves the aorta and its major branches. Renal arteries are frequently involved, usually with renovascular hypertension. The prevalence of TA in Arabs is low. A study of the epidemiological and clinical features of TA in Arabs included 197 identified patients between 1995 and 2012 and none of them was Libyan. We report a 61‑year‑old Libyan woman in whom TA manifested with hypokalemia and arterial hypertension. Previous ultrasound showed renal size asymmetry raised the possibility of renal artery stenosis. The diagnosis of TA was confirmed by magnetic resonance angiography, which showed a thickened abdominal aortic wall, occlusions of the left renal artery and left common iliac artery, stenosis of the right common iliac artery, and stenosis of both subclavian arteries. TA is rarely encountered in Arabs. However, the disease must be considered in patients who present with renovascular hypertension, in a context of other autoimmune disorders. arabic 6 English 33
Hawa Juma El-Shareif(1-2019)
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Clinicopathological features of differentiated thyroid carcinoma referred to radioiodine therapy at Tripoli Medical Center

Objectives: The objective of this study is to study the demographic, clinicopathological features, and geographical distribution of differentiated thyroid cancer (DTC) among Libyan patients referred from all parts of the country to the nuclear medicine department, for radioactive iodine (RAI) therapy.Materials and Methods: Retrospective review of medical records of 265 patients with differentiated thyroid carcinoma (DTC) referred to RAI therapy in the Nuclear Medicine Branch‑Tripoli Medical Center, in the period from May 2005 to October 2010. The data analyzed included sex, age at the time of diagnosis, the city of residence, pathological diagnosis, the extent of disease, and types of treatment.Results: There were 225 (84.9%) females and 40 (15.1%) males giving a sex ratio of 5.6:1. The mean age of males at diagnosis was 51.2 ± 14.8 (range 24–78) years and  the  mean age  of  the  females was  44.6 ± 15.6 (range 10–95) years. Two  hundred and  twenty‑three (84.2%) had  papillary thyroid cancer (PTC), 31 (11.7%) had  follicular thyroid cancer, 3 (1.1%) had  Hurthle cell  thyroid cancer, and  2 (0.8%) had follicular‑insular thyroid cancer. About 43 (16.2%) had  a  history of  multinodular goiter, and  3 (1.1%) Hashimoto’s thyroiditis. From data  collected, cervical lymph node metastases were found in 45 (17.0%), and distal metastases in 27 (10.2%).Conclusions: PTC was the most common type of DTC. DTC was more common among females. The current study showed that the disease tends to occur at an older age, and with less cervical lymph node metastases than previously reported.
Hawa Juma El-Shareif(3-2018)
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The diagnostic performance of chest computed tomography scanning in the diagnosis of coronavirus disease 2019 compared to polymerase chain reaction: A retrospective study of 1240 cases from Tripoli University Hospital, Libya

OBJECTIVE: The increasing prevalence of suspected cases of coronavirus disease 2019 (COVID-19) presenting to emergency departments (EDs) requires a rapid and reliable triaging tool. The diagnostic performance of chest computed tomography (CT) has yet to be validated for triaging cases in the ED. We aimed to assess the diagnostic performance of chest CT compared to GeneXpert Xpress Xpert severe acute respiratory syndrome coronavirus 2 test in rapidly diagnosing COVID-19 among patients with respiratory symptoms presenting to the ED. MATERIALS AND METHODS: This was a retrospective, single-center study at Tripoli University Hospital including cases with respiratory symptoms who underwent chest CT as well as polymerase chain reaction (PCR) testing for suspected COVID-19 between May 18 and August 18, 2020. RESULTS: A total of 1240 cases were included, among whom 570 had radiologically evident COVID-19 on chest CT (46%). Five hundred and sixty-five cases had positive PCR results (45.6%), of whom 557 had radiologically evident COVID-19 on chest CT (97.7%). The calculated accuracy, sensitivity, specificity, positive predictive value, and negative predictive value were 98%, 98.5%, 98%, 97.7%, and 98.8%, respectively, in relation to the PCR results. CONCLUSION: During the current pandemic, chest CT is a quick and reliable diagnostic tool for COVID-19 in the ED.
Nader Shalaka(11-2021)
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