Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 Antibodies among People Living with HIV: A Cross-sectional Study from Tripoli University Hospital
Background/Aims: Patients with preexisting morbidities(e.g., malignancy, posttransplant, and heart failure) are recognized to be at increased
risk of severe acute respiratory syndrome coronavirus‑2 (SARS‑CoV‑2) infection, as well as increased risk of mortality after infection. However,
there are conflicting data on the susceptibility and prevalence of infection among people living with HIV (PLWH), with higher, lower, and equal
prevalence to the general population were reported. The aim of this study was to assess the prevalence of SARS‑CoV‑2 antibodies among PLWH
who are attending clinical care at the Department of Infectious Diseases of Tripoli University Hospital. Materials and Methods: A cross‑sectional
study conducted during the period from October 01, 2021 to December 01, 2021 at the (Department of Infectious Diseases) outpatient clinic
of Tripoli University Hospital. The OnSite Coronavirus Disease 2019 IgG/IgM Rapid Test (CTK Biotech, San Diego County, California, USA)
was used to determine the presence of antibodies against the spike protein of SARS‑CoV‑2 in the collected serum samples. The test results
were reported as “Negative” or “Positive” as per the manufacturer’s instructions. Results: A total of 108 PLWH were included in the study.
Sixty‑nine (64%) were male, and the mean age for participants was 44 years. Specific IgG/IgM antibodies for SARS‑CoV‑2 were detected in
31 individuals, representing a seroprevalence of 28.7%. Conclusions: High seroprevalence of SARS‑CoV‑2 antibodies among nonvaccinated
PLWH attending clinical care at Tripoli University Hospital. They require pritorization on vaccination and boosting
Nader Shalaka(12-2021)
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