Exposures to a wide variety of environmental substances are negatively associated with many biological cell systems both in humans and rodents. Trichloroethane (TCE), a ubiquitous environmental toxicant, is used in large quantities as a dissolvent, metal degreaser, chemical intermediate, and component of consumer products. This increases the likelihood of human exposure to these compounds through dermal, inhalation and oral routes. The present in vivo study was aimed to investigate the possible cellular and molecular etiology of liver abnormality induced by early exposure to TCE using a murine model. The results showed a significant increase in liver weight. Histopathological examination revealed a TCE-induced hepatotoxicity which appeared as heavily congested central vein and blood sinusoids as well as leukocytic infiltration. Mitotic figures and apoptotic changes such as chromatin condensation and nuclear fragments were also identified. Cell death analysis demonstrates hepatocellular apoptosis was evident in the treated mice compared to control. TCE was also found to induce oxidative stress as indicated by an increase in the levels of lipid peroxidation, an oxidative stress marker. There was also a significant decrease in the DNA content of the hepatocytes of the treated groups compared to control. Agarose gel electrophoresis also provided further biochemical evidence of apoptosis by showing internucleosomal DNA fragmentation in the liver cells, indicating oxidative stress as the cause of DNA damage. These results suggest the need for a complete risk assessment of any new chemical prior to its arrival into the consumer market.
Mohamed M. Al-Griw, Rabia O. Alghazeer, S. A. Al-Azreg, Emad M. Bennour(9-2016)

Objective Healthcare workers, particularly those working in departments that provide care for patients with coronavirus disease 2019 (COVID-19), are at a higher risk of this contagious disease than those who work in other departments. The aim of this study was to assess the psychological status of healthcare workers during the COVID-19 outbreak, which has compounded Libya's existing civil war-related problems. Methods A multi-center cross-sectional survey on depressive symptoms, anxiety symptoms, and abuse was conducted. The Hospital Anxiety and Depression Scale (HADS) was used to measure the prevalence of anxiety and depressive symptoms among healthcare workers. Results The data of 745 eligible healthcare workers from 15 hospitals were analyzed. Depressive and anxiety symptoms were compared to the basic characteristics of the participants to determine the association. A total of 420 (56.3 … arabic 17 English 93
Muhammed Elhadi, Ahmed Zaid(1-2020)

Asthma has been considered the most common chronic respiratory disease affecting children and is involved in .different diagnoses of acute bronchiolitis in first year of life Therefore, this research has been conducted to explore the relationship between asthma and bronchiolitis on known asthmatics aging from 6months old to 16 years old frequenting the asthma clinic Tripoli Children Hospital for .)regular follow ups for 3 months (January, February, and march of 2004 The aim of this study: To ascertain the percent (prevalence)of bronchiolitis patients who will develop]e asthma .symptoms later on Conclusively there has been a strong relationship between asthma and bronchiolitis in a way that bronchiolitis pre- .disposes to asthma in 53.5% of patients especially in whom had a family history of allergy
Hisham Mukhtar Alrabty(4-2020)