The hepatotoxicity and nephrotoxicity of chlorpyrifos (CPF) and imidacloprid (IMC) insecticides were experimentally studied in layer chickens, taking into account the patho-biochemical alterations. The LD50 values estimated were 41 mg/kg bw and 104.1 mg/kg bw for CPF and IMC, respectively. The plasma cholineesterase enzyme was severely inhibited in chickens given a single dose of CPF at a rate of 55 mg/kg bw via oral gavage, while it remained unchanged in chickens given IMC at rate of 139 mg/kg bw via similar route. The activities of liver function enzymes viz. AKP, ALT and AST were significantly increased in chickens of CPF and IMC groups. Uric acid level was significantly increased and cholesterol level was only significantly reduced in the plasma of chickens administrated CPF. Plasma glucose values in chickens given CPF as well as in chickens given IMC were significantly increased at (P
Abdulwahab Kammon(1-2010)

Abstract Avian paramyxovirus-1 (APMV-1) is the causative agent of Newcastle Disease which affects many species of birds leading to high mortality and heavy economic losses among poultry industry worldwide. Newcastle disease is endemic in Libya with frequent outbreaks occurring in commercial and backyard poultry. APMV-1 was isolated and characterised during the outbreak in 2013. In current study, we report another Newcastle disease outbreak that emerged in backyard chickens and pigeons in Alzintan city on March 2015. Two viruses were detected in cloacal swabs from backyard chickens, namely APMV-1/Libya/15VIR5368/2015 and APMV-1/Libya/15VIR5371/2015. Genetic sequencing of these viruses revealed the presence of velogenic APMV-1 belonging to genotype VIIi genetically similar to the viruses isolated on 2013. During the same period, neurologic signs and mortality were noticed in pigeons. Samples of brain tissue were tested by rRT-PCR which revealed presence of velogenic APMV-1 belonging to lineage 4A (GKKRKR*F Lin.4A) or genotype VIb. To the best of our knowledge, this is the first report of the detection and molecular characterization of APMV-1 in a pigeon in Libya. The phylogenetic analysis of the F gene showed 86% identity to isolates from Iran and Egypt. This study may indicate the circulation of APMV-1 within backyard birds and pigeons which may present a threat to commercial poultry. Considering these findings, vaccination of backyard birds and pigeons and further epidemiological studies are strongly strongly recommended. arabic 19 English 111
Abdulwahab Kammon, Isabella Monne, Abdulatif Asheg , Giovanni Cattoli (1-2018)

as attached
Abdulwahab Kammon(1-2022)